Résumé

P032

Hyperprolactinemia in post menopausal women: a case report

I. Barka*^a (Dr), S. Ouerdeni^a (Dr), Y. Hasni^a (Dr), I. Slim^a (Dr), A. Maaroufi^a (Pr), M. Kacem^a (Pr), M. Chaieb^a (Pr), K. Ach^a (Pr), L. Chaieb^a (Pr)

^a CHU,FARHAT HACHED, Sousse, TUNISIE

* inesbarka14@gmail.com

Background:

The incidence of hyperprolactinemia in women peaks during the 3rd-4th decade and then greatly decreases after the menopause. It has been linked to secondary osteoporosis, weight gain and insulin resistance, which can be ameliorated following medical treatment. Although relatively rare, prolactinomas can be observed in post-menopausal women

Case report:

Here, we report the case of a 57 years old female with a history of cervical pain treated by neuroleptic , who presented with secondary amenorrhea and galactorrhea for 2 years ,persisting despite the withdraw of medication On examination, her body mass index was 32 kg/m2 ,her blood pressure was 130/80 mmHg without goiter or hyperandrogenic signs . Her prolactin level was 2735 µUI / L(N=130-500), TSH was 0,88 µUI/ml, and FSH = 15,1mUI/ml , LH= 4,1mUI/ml . The MRI showed an adenoma of 8mm. Her bone mass density showed a low bone strength . She was treated by dopamine agonist with a favorable issue.

Conclusion:

This observation highlights the importance of considering the diagnosis of hyperprolactinemia due to pituitary adenoma mainly in premenopausal women; Symptoms can be confused with those of menopause responsible for a diagnosis delay and Medical treatment should be discussed based on osteoporosis and neoplasic risks

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